PNA Origami

Required Availability

Spring 2019 | Summer 2019 | Fall 2018

Preferred Majors

Biochemistry | Biochemistry/Biology | Biochemistry/Chemistry | Chemical Engineering | Chemistry

Keywords

peptide nucleic acid | nanostructures

Description

Peptide nucleic acids (PNAs) combine the nucleobases from DNA and a peptide backbone. These molecules can bind to DNAs, RNAs and PNAs with complementary sequences through Watson-Crick base pairing. These interactions can be used to build nanostructures ("DNA origami"). We will use the structural diversity of the PNA backbone to create materials with an expanded repertoire of hydrophilic, hydrophobic and charged surfaces.

Special Skills

basic organic lab techniques

Contact Phone #

N/A

Contact Email

swoski@ua.edu

Research Website

N/A